过去,急性白血病多在6个月以内死亡。1948年Farber等介绍了抗叶酸(Folic acidantagonists),这是治疗急性白血病等一个有效的化疗药物;以后,随之有不少药物被发现,如1953年Burchenal发现抗嘌呤药——6巯基嘌呤(6MP);1949年Pearson提出皮质类固醇对急性白血病有效,于 In the past, acute leukemia and more died within 6 months. In 1948, Farber et al. Introduced Folic acidantagonists, an effective chemotherapeutic drug for the treatment of acute leukemias; later, many drugs were discovered, as in 1953 Burchenal found anti-purinergic drugs, 6-mercaptopurine 6MP); 1949 Pearson proposed corticosteroids effective in acute leukemia in