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识别和抗御微生物感染是多细胞生物的本能。在进化关系很远的生物中 ,如人类和果蝇 ,甚至植物 ,都存在这种天然免疫识别和防御机能 ,表明许多宿主防御基因及其产物具有共同的古老的起源 ,但又存在结构和功能的多样性。本文描述了一些哺乳动物和昆虫中有关于免疫识别的蛋白并调查了其同系物的进化分布情况。分析证实了哺乳动物和昆虫的天然免疫系统重要结构和功能的多样性 ,列举了一些关于蛋白进化趋势的例子
Identifying and defending microbial infections is the instinct of multicellular organisms. This natural immune recognition and defense function exists in organisms that are evolutionarily distant, such as humans and fruit flies, and even plants, suggesting that many host defense genes and their products share a common ancient origin but are structurally and functionally Diversity. This article describes some mammals and insects that have immunological recognition of proteins and investigated the evolutionary distribution of their homologs. The analysis confirms the diversity of important structures and functions of the natural immune system in mammals and insects, cites some examples of protein evolutionary trends