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目的 :观察柴芩达原饮联合西医疗法治疗轻症急性胰腺炎的效果。方法 :选取132例轻症急性胰腺炎辨证属湿遏热伏、邪阻膜原证的患者,随机分为观察组70例和对照组62例。2组均按常规西医疗法治疗,观察组禁食不禁药,加用柴芩达原饮治疗,观察治疗14天。记录2组患者的肠鸣音恢复正常时间,恶心、呕吐、腹痛等症状的缓解时间,观察并记录血谷丙转氨酶(ALT)、白细胞计数(WBC)、淀粉酶(AMY)、尿素氮(BUN)、C-反应蛋白(CRP)的变化与恢复正常的时间、住院时间,监测安全性指标。结果:治疗后,观察组总有效率(97.14%)高于对照组(74.19%),差异有统计学意义(P<0.05)。2组ALT、WBC、AMY、BUN、CRP水平均较治疗前下降(P<0.05),观察组WBC、AMY、BUN、CRP水平均低于对照组(P<0.05)。观察组恶心呕吐缓解时间、腹痛缓解时间,肠鸣音、WBC、AMY、BUN、CRP恢复正常时间与住院时间均短于对照组,差异均有统计学意义(P<0.05)。结论:在常规西医疗法基础上加用柴芩达原饮治疗辨证为湿热之邪伏阻于膜原的轻症急性胰腺炎患者,能更为迅速地改善症状,缩短病程,安全性高,疗效优于单纯使用西医疗法治疗。
Objective: To observe the effect of Chai Qin Dali Yin combined with Western medical treatment of mild acute pancreatitis. Methods: A total of 132 patients with mild acute pancreatitis were randomly divided into observation group (n = 70) and control group (n = 62). Both groups were treated according to the conventional western medicine. The fasting group in the observation group could not help but use Chaiqinda original drink to treat for 14 days. The remission time of nausea, vomiting, abdominal pain and other symptoms were recorded and the ALT, WBC, AMY, BUN ), C-reactive protein (CRP) changes with the recovery of normal time, hospital stay, monitoring of safety indicators. Results: After treatment, the total effective rate in observation group (97.14%) was higher than that in control group (74.19%), the difference was statistically significant (P <0.05). The levels of ALT, WBC, AMY, BUN and CRP in 2 groups were lower than those before treatment (P <0.05). The levels of WBC, AMY, BUN and CRP in observation group were lower than those in control group (P <0.05). The nausea and vomiting relief time, abdominal pain relief time, bowel sounds, WBC, AMY, BUN and CRP recovery time and hospital stay in the observation group were all shorter than those in the control group, with statistical significance (P <0.05). Conclusion: Based on the conventional western medicine, Chaiqindaoyin Decoction is used to treat patients with mild acute pancreatitis with dampness and heat resistance, which can improve the symptoms more quickly, shorten the course of the disease, improve the safety and curative effect. Better than simply using Western medical treatment.