本文介绍了近年来具有抗菌活性的天然酚酸类化合物的研究进展。内容包括具有抗菌活性的中草药酚、酸类抗菌成分,其结构与疗效之间的关系及作用机制的探讨。认为有针对性的从具有清热解毒作用的传统中草药中寻找活性更好的成分和对活性成分进行结构改造,仍是寻找抗菌药物值得探索的一个方向。 This article describes the research progress of natural phenolic compounds with antibacterial activity in recent years. The content includes the antibacterial activity of Chinese herbal phenols, acid antibacterial components, the relationship between its structure and efficacy and the discussion of the mechanism of action. It is considered that targeted search for more active ingredients and structural modifications of active ingredients from traditional Chinese herbal medicines that have a detoxifying and detoxifying effect is still a direction that is worth looking for.