Short-term efficacy of laparoscopy-assisted vs open radical gastrectomy in gastric cancer

来源 :World Journal of Gastrointestinal Surgery | 被引量 : 0次 | 上传用户:helinjue
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AIM:To investigate the short-term benefits of laparoscopic radical gastrectomy(LARG)and open radical gastrectomy(ORG)in patients with gastric cancer.METHODS:A total of 400 patients with gastric cancer aged≤65 years who were treated at General Hospital of Lanzhou Military Region were enrolled.Among these,200 patients underwent LARG between October2008 and August 2012(LARG group);and 200 patients underwent ORG between March 2000 and September2008(ORG group).The short-term therapeutic benefits between the two groups were analyzed.RESULTS:The LARG procedure offered significantly better benefits to the patients compared to the ORG procedure,including less intraoperative blood loss(103.1±19.5 mL vs 163.0±32.9 mL,P<0.0001),shorter postoperative hospital stay(6.8±1.2 d vs 9.5±1.6 d,P<0.0001),less frequent occurrence of postoperative complications(6.5%vs 13.5%,P=0.02),shorter time to mobilization(1.0±0.3 vs 3.3±0.4 d,P<0.0001),shorter time to bowel opening(3.3±0.7 d vs 4.5±0.7 d,P<0.0001),and shorter time to normal diet(3.0±0.4 vs d 3.8±0.5 d,P<0.0001).However,LARG required a longer time to complete than the ORG procedure(192.3±20.9 min vs 180.0±26.9 min,P<0.0001).CONCLUSION:Compared to ORG,LARG is safer,more effective,and less invasive for treating gastric cancer,with better short-term efficacy. A investigate the short-term benefits of laparoscopic radical gastrectomy (LARG) and open radical gastrectomy (ORG) in patients with gastric cancer. METHODS: A total of 400 patients with gastric cancer aged ≤65 years who were treated at General Hospital of Lanzhou Military Region were enrolled. Among these, 200 patients underwent LARG between October 2008 and August 2012 (LARG group); and 200 patients underwent ORG between March 2000 and September 2008 (ORG group). The short-term therapeutic benefits between the two groups were analyzed .RESULTS: The LARG procedure offered significantly better benefits to the patient compared to the ORG procedure, including less intraoperative blood loss (103.1 ± 19.5 mL vs 163.0 ± 32.9 mL, P <0.0001), shorter postoperative hospital stay (6.8 ± 1.2 d vs Shorter time to mobilization (1.0 ± 0.3 vs. 3.3 ± 0.4 d, P <0.0001), shorter time to mobilization (6.5 ± vs 13.5%, P = 0.02) Bowel opening (3.3 ± 0.7 d vs 4.5 ± 0.7 d, P <0.0 001), and shorter time to normal diet (3.0 ± 0.4 vs d 3.8 ± 0.5 d, P <0.0001) .Wever, LARG required a longer time to complete than the ORG procedure (192.3 ± 20.9 min vs 180.0 ± 26.9 min, P <0.0001). CONCLUSION: Compared to ORG, LARG is safer, more effective, and less invasive for treating gastric cancer, with better short-term efficacy.
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