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至今已发现胃肠胰能分泌10余种激素,且大部分已弄清其化学结构,其中几种已开始应用于临床。因此,胃肠胰作为一个内分泌器官已引起人们广泛的重视,本文仅就临床上应用的几种主要的激素作一介绍。一、胃泌素(一)生成部位、化学结构和作用胃泌素主要由胃窦及十二指肠近端粘膜的 G 细胞分泌,其化学结构为17个氨基酸组成的多肽(G-17),第12位酪氨酸未硫酸化的称胃泌素Ⅰ,硫酸化的称胃泌素Ⅱ(分子量分别为2,096和2,176),
It has been found that gastrointestinal Pancreas can secrete more than 10 kinds of hormones, and most of them have been clarified its chemical structure, several of which have begun to be used clinically. Therefore, gastrointestinal pancreas as an endocrine organ has attracted widespread attention, this article only on the clinical application of several major hormones for an introduction. First, the gastrin (a) the formation of the site, the chemical structure and role of gastrin mainly by the gastric antrum and proximal duodenal mucosa of G cells, the chemical structure of a polypeptide of 17 amino acids (G-17) , The 12th tyrosine unsulfated gastrin I, the sulfated gastrin II (2,096 and 2,176, respectively)