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本文报告115例各型肾小球疾病使用双夹心酶免疫测定法检测尿视黄醇结合蛋白(RBP)含量的临床意义。其中原发性肾病及单纯性血尿各30例,紫癜性肾炎和过敏性紫癜各20例,胰岛素依赖性糖尿病10例,肾功能不全5例。检测结果,肾病、过敏性紫癜、糖尿病和肾功能不全组与对照组比较有显著差异性(P<0.01),紫癜性肾炎与对照组比较有差异性(P<0.05)。尿RBP含量增加也反映了各型肾小球疾病同时伴有肾近曲小管受损,值得重视。
This article reports 115 cases of various types of glomerular disease using double sandwich enzyme immunoassay detection of retinol binding protein (RBP) in clinical significance. Including 30 cases of primary renal disease and simple hematuria, 20 cases of purpura nephritis and allergic purpura, 10 cases of insulin-dependent diabetes mellitus, renal insufficiency in 5 cases. There were significant differences between the two groups (P <0.01), nephritis, Henoch-Schonlein purpura, diabetic and renal dysfunction group and control group (P <0.05). Increased urine RBP content also reflects the various types of glomerular disease accompanied by proximal renal tubule damage, it is worth attention.