1991年1～3月,无锡市发生了一种以发热和猩红热样皮疹为主要症状的疾病,部分病人伴有呕吐、腹泻,严重者出现休克和肝、心、肾功能损害。疫情迅速波及整个市区和近郊区,共报告823例,罹患率为81.16/10万。现将流行病学调查资料分析如下:调查方法(一)各级医疗单位根据统一的标准进行诊断,并填写传染病报告卡,由市卫生防疫站登记。(二)诊断标准:出现下列症状,诊断本病:1.突然起病,发热、咽痛继出现猩红热样皮疹,排除其他原因引起者;2.发热伴有全身肌肉酸痛,呕吐、腹泻和低血压症状;3.合并出现肝、心、肾脏器功能损害;4.中性白细胞计数增高,青霉素等抗生素治疗有效。(三)按随机抽样的原则,对各级医疗单位报 From January to March 1991, a disease characterized by fever and scarlet fever-like rash occurred in Wuxi City. Some patients were accompanied by vomiting and diarrhea. Severe shock, liver, heart and kidney damage occurred. The epidemic quickly spread to the entire urban area and suburban areas, a total of 823 cases were reported, the attack rate was 81.16 / 100000. Epidemiological survey data are now as follows: Method of investigation (A) at all levels of medical units in accordance with a unified standard for diagnosis, and fill in the infectious disease report card, registered by the city health and epidemic prevention station. (B) of the diagnostic criteria: the following symptoms, the diagnosis of the disease: 1. Sudden onset, fever, sore throat following the emergence of scarlet fever-like rash, excluding other causes; 2 fever accompanied by body muscle soreness, vomiting, diarrhea and low Blood pressure symptoms; 3 combined with liver, heart and kidney dysfunction; 4 neutrophil count increased penicillin and other antibiotics effective. (C) according to the principle of random sampling, medical units at all levels reported