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老年慢性便秘是老年人最常见的病症之一,主要病机在于肾虚,与年龄增长呈正相关。我们从治本入手,以补肾濡润的肉苁蓉为君,养血生津的当归为臣,增液行舟的生地为佐,润肠通便的火麻仁、郁李仁为使,组方成补肾润肠汤。在润肠汤的基础上进行剂型改革,制成冲剂,经各项质控检测符合标准后用于临床。通过309例的临床验证,结果显示,有效率达96.7％。便秘的五项观察指标均有显著改善。经统计学处理,与对照组比较,有非常显著性差异(P<0.001),本冲剂不仅有早期效果,还有较好的后效,停药十天,仍保持一定的疗效,而且使用方便,无毒副作用。以传统中药肉苁蓉为主补肾求本,调整人体阴阳气血和肚腑功能,为本药的突出特点。
Chronic constipation in the elderly is one of the most common diseases in the elderly. The main pathogenesis is kidney deficiency, which is positively correlated with age. We started with a permanent cure to treat the kidneys with radix Cistanche as a rule. The nourishing blood is used as an adjunct to the Chinese angelica. The fluid-enriched urine is used as a source of saliva, the laxative of the hemp kernel and Yu Liren are used, and the formula is a kidney easing. soup. The reform of the dosage form on the basis of the Runchang Soup is made into granules, which are used for clinical purposes after the quality control tests meet the standards. Through clinical validation of 309 cases, the results showed that the effective rate was 96.7%. The five observational indicators of constipation have improved significantly. After statistical analysis, compared with the control group, there was a very significant difference (P<0.001). The granules not only had early effects, but also had good aftereffects. After 10 days of withdrawal, they still maintained a certain degree of efficacy, and were easy to use. No toxic side effects. The traditional Chinese medicine cistanche is mainly used to supplement the kidney and adjust the body’s yin and yang qi, blood and intestine function, which is the prominent feature of this medicine.