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呼吸机相关性肺炎(VAP)是指经气管插管或气管切开行机械通气48小时后发生的肺部感染~([1,2])。VAP是重症医学科(ICU)内机械通气患者最常见的感染性疾病之一~([3]),在国内外ICU内的发病率为9%~40%,病死率高达24%~76%。并发VAP患者机械通气时间、ICU住院时间和总住院时间明显延长,住院费用增加。本研究旨在建立体外人体气道模型,通过观察体位,分泌物粘稠度,潮气量和流速对气囊上滞留物
Ventilator-associated pneumonia (VAP) is a pulmonary infection that occurs 48 hours after mechanical ventilation through an endotracheal or tracheostomy line ([1,2]). VAP is one of the most common infectious diseases in patients with mechanical ventilation in the intensive care unit (ICU). [3] The incidence of ICU is 9% -40% within the ICU at home and abroad, and the mortality rate is as high as 24% -76% . Complications of VAP patients with mechanical ventilation, ICU length of stay and hospital stay was significantly prolonged, hospital costs increased. This study aimed to establish a human airway model in vitro, by observing body position, secretions viscosity, tidal volume and flow rate of air bag on the retentate