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目的：探究十二指肠溃疡患者运用泮托拉唑肠溶片治疗的临床成效。方法：选取我院2015年10月-2016年6月入院的十二指肠溃疡患者60例，按照随机分组法分为观察组和对照组，每一组30人。对照组患者运用奥美拉唑进行治疗，观察组运用泮托拉唑肠溶片治疗。对两组患者临床治疗成效进行对比。结果：观察组患者治疗总有效率显著优于对照组。两组之间差异明显（P<0.05），具有统计学意。结论：十二指肠溃疡患者运用泮托拉唑肠溶片治疗的临床成效十分显著，应在临床大力推广应用。“,”Objective:To explore the clinical effectiveness of the use of patients with duodenal ulcer Pantoprazole enteric-coated tablets treatment.Methods: My hospital in October 2015 - duodenal ulcer patients admitted to hospital in June 2016, 80 cases, according to randomized divided into observation group and control group, each group of 40 people. The control group of patients using omeprazole treatment, observation group using pantoprazole enteric-coated tablets for treatment. The clinical outcome of the treatment groups were compared.Results:The total effective rate of observation group was significantly better than the control group. Significant differences between the two groups (P <0.05), with statistical significance.Conclusion:The use of patients with duodenal ulcer Pantoprazole enteric-coated tablets therapy clinical effectiveness is very significant, should be vigorously promoted in the clinical application.