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目的：探讨心理干预对癌症放疗患者焦虑抑郁情绪、应对方式及免疫功能的影响。方法将60例合并焦虑抑郁障碍的放疗癌症患者按照随机数字表法分为两组，每组30例，均予以常规放疗及健康教育，干预组在此基础上联合综合心理干预，观察2个月。干预前后应用艾森克人格问卷、应对方式问卷、焦虑自评量表、抑郁自评量表进行测评分析，并测定免疫功能。结果两组艾森克人格问卷的神经质维度分均显著高于常模(P 0.05)。干预后干预组焦虑自评量表、抑郁自评量表总分较干预前显著降低(P <0.01)，且显著低于对照组(P <0.01)；积极应对方式评分较干预前显著升高，且显著高于对照组(P<0.01)；消极应对方式评分较干预前显著下降，且显著低于对照组(P <0.01)；各项免疫指标改善显著优于对照组(P <0.01)。结论癌症患者具有较高的神经质特质，心理干预能显著改善癌症放疗患者的焦虑抑郁情绪，促使患者更多的采用积极应对方式，显著提高患者细胞免疫功能。“,”Objective To explore the impact of psychological intervention on anxiety-depressive emotions, coping styles and immune functions of cancer patients undergoing radiotherapy.Methods Sixty cancer pa-tients with anxious-depressive disorder were assigned to two groups of 30 ones each according to random number table,both groups received routine radiotherapy and health education,and on this basis interven-tion group was plus comprehensive pyshological intervention for 2 months.Assessments were conducted with the Eysenck Personality Questionnaire (EPQ),Coping Style Questionnaire (CSQ),Self-rating Anxi-ety Scale (SAS),and Self-rating Depression Scale (SDS)before and after intervention,and immune func-tions determined.Results N scores of the EPQ in both groups were significantly higher compared with norm (P 0.05).After intervention the SAS and SDS total score lowered more significantly compared with pre-intervention in intervention group (P <0.01)and were significantly lower than in control group (P < 0.01 );positive coping score heightened more significantly compared with pre-intervention in intervention group (P <0.01)and was significantly higher than in control group (P <0.01);negative coping score lowered more significantly compared with pre-intervention in intervention group (P <0.01)and was significantly lower than in control group (P <0. 01).Intervention outstripped control group in the improvements of all indexes of immune functions (P <0.01).Conclusion Cancer patients have higher neuroticism trait,psychological intervention could notably improve anxiety-depressive emotions of cancer patients undergoing radiotherapy,promote patients to adopt more positive coping styles,and boost patients’immune functions notably.