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目的:探讨儿童复发性呼吸道乳头状瘤病(JO-RRP)肿瘤范围的量化评估方法的临床应用。方法:根据肿瘤范围大小分为3级分值(1分,2分及3分),评估68例JO-RRP患儿共238次手术,内镜下观察患儿22个呼吸和消化道的解剖亚区的肿瘤范围,计算积分;量化反映JO-RRP的分布特点及病情演变。结果:本组患儿肿瘤范围的积分在2~20分,7~14分占64.3%。全部患儿均有喉部受累,其中声带和室带是最常见的受累部位,鼻、咽、硬腭、气管、支气管、双肺和食管等受累较少见;随着手术治疗次数增多,肿瘤范围积分有下降趋势,与JO-RRP的临床特点相符。结论:以肿瘤范围为依据的量化评估法客观准确地反映了JO-RRP病变程度和临床疗效,是个科学而方便的方法,临床应用价值高,值得推广。
Objective: To investigate the clinical application of quantitative assessment of tumor range in recurrent respiratory papillomatosis (JO-RRP) in children. Methods: According to the size of the tumor, the patients were divided into 3 grades (1, 2 and 3 points). A total of 238 operations were performed in 68 cases of JO-RRP, and 22 cases of respiratory and digestive tract anatomy Sub-region of the tumor range, calculate the integral; quantitative reflect the distribution of JO-RRP and disease evolution. Results: The score of tumor in this group ranged from 2 to 20 and 64 to 7% from 7 to 14. All children had laryngeal involvement, of which vocal cord and ventricular band are the most common sites involved, nasopharynx, pharynx, palate, trachea, bronchi, lungs and esophageal involvement is less common; with the increase in the number of surgical treatment, the tumor score There is a downward trend, consistent with the clinical features of JO-RRP. Conclusion: The quantitative assessment based on the tumor range objectively and accurately reflects the degree of JO-RRP lesions and clinical efficacy. It is a scientific and convenient method, which has high clinical value and worthy of promotion.