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目的探讨妊娠期甲状腺功能亢进(甲亢)的治疗情况对新生儿的影响。方法选取2007年1月至2011年8月在我院分娩的妊娠合并甲亢孕妇64例,根据孕妇甲亢治疗情况分为甲亢控制组(44例)与未控制组(20例),对两组甲亢孕妇所分娩的新生儿甲状腺功能与生长发育情况进行分析。结果甲亢未控制组新生儿甲亢、甲状腺功能减低、早产儿、小于胎龄儿发生率分别为35.00%、25.00%、50.00%、20.00%,甲亢控制组分别为4.55%、2.27%、6.82%、0.00%,两组新生儿甲状腺功能异常、早产及小于胎龄儿发生率的差异均有统计学意义(P<0.05,P<0.01)。结论对妊娠期甲亢患者进行积极有效的治疗能够显著改善新生儿的健康水平。
Objective To investigate the effect of treatment of hyperthyroidism (hyperthyroidism) during pregnancy on newborns. Methods Sixty-four pregnant women with hyperthyroidism who were delivered in our hospital from January 2007 to August 2011 were divided into hyperthyroidism control group (n = 44) and uncontrolled hypertensive group (n = 20) according to the treatment of hyperthyroidism. Analysis of thyroid function and growth of newborns delivered by pregnant women. Results The incidences of neonatal hyperthyroidism and hypothyroidism in uncontrolled hyperthyroidism group were 35.00%, 25.00%, 50.00% and 20.00% respectively. The incidences of preterm and small gestational age were 4.55%, 2.27% and 6.82% in hyperthyroidism control group, 0.00%. There was significant difference in the incidence of thyroid dysfunction, premature birth and small gestational age in both groups (P <0.05, P <0.01). Conclusion The positive and effective treatment of hyperthyroidism in pregnancy can significantly improve the health of newborns.