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目的评价生物反馈、聚乙二醇4000综合治疗成人功能性排便障碍(FDD)的疗效。方法64例FDD患者分成3组,分别接受生物反馈(BF)(n=20)、聚乙二醇4000(PEG4000)(n=23)及两者联合治疗(n=21),治疗后1周内及3个月时比较3组病例的临床疗效。结果治疗后1周内3组病例总有效率比较差异无显著性(P>0.05),显效率差异有显著性(P<0.05),其中PEG4000组和综合治疗组均明显高于BF组(P<0.05);治疗后3个月时总有效率和显效率差异均有统计学意义(P<0.05),其中BF组和综合治疗组的总有效率及显效率均明显高于PEG4000组(P<0.05)。结论BF联合PEG4000治疗成人FD具有良好的短、中期疗效,是一种有效的治疗方法。
Objective To evaluate the efficacy of biofeedback and polyethylene glycol 4000 in the treatment of adult functional defecation disorder (FDD). Methods Sixty-four patients with FDD were divided into 3 groups: one group received biofeedback (BF) (n = 20), PEG 4000 (n = 23) Within 3 months and 3 months when comparing the clinical efficacy of 3 cases. Results There was no significant difference in the total effective rate (P> 0.05) between the three groups within 1 week after treatment, and the significant difference was significant (P <0.05). The PEG4000 group and the combination treatment group were significantly higher than the BF group (P <0.05). The total effective rate and markedly effective rate at 3 months after treatment were significantly different (P <0.05). The total effective rate and markedly effective rate in BF group and comprehensive treatment group were significantly higher than those in PEG4000 group (P <0.05) <0.05). Conclusion BF combined with PEG4000 in the treatment of adult FD has a good short-term, medium-term efficacy, is an effective treatment.