响应面法优化一叶种子壳中一叶碱的提取工艺

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目的:利用响应面分析法优化一叶种子壳中一叶碱的提取工艺参数。方法:采取酸水浸泡提取法、离子交换法及索氏抽提法结合的方法对一叶种子壳中一叶碱提取进行优化。经过单因素法与响应面 Box-Behnken 法选择初始参数,之后利用 Design-Expert 软件进行二次回归分析对参数进一步优化。结果:最优参数为提取次数3次,乙醇浓度85%,酸浓度4.7‰。结论:所优选的提取工艺具有良好的可行性。
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