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目的探讨手足口病(HFM;;DOI:10.3969/j.issn.)危重症发生相关的危险因素,寻找发生HFM;;DOI:10.3969/j.issn.危重症的早期预警指标。方法对2010年3-9月新乡市中心医院73例HFM;;DOI:10.3969/j.issn.危重症患儿和新乡市传染病医院90例重症HFM;;DOI:10.3969/j.issn.患儿临床资料进行单因素和多因素分析。HFM;;DOI:10.3969/j.issn.诊断标准按照我国卫生部印发的《手足口病诊疗指南2010年版》的临床诊断标准。结果重症症HFM;;DOI:10.3969/j.issn.患儿发生危重症前表现出以下特点:持续高热(≥39℃)、精神萎靡或嗜睡、肢体抖动或震颤、血压持续高、心率快、血糖高、呼吸节律改变、末梢循环差、外周血白细胞计数升高、双肺闻及啰音等。采用单因素行×列卡方及二分类多因素Logistic分析发现,血压持续高、心率增快、血糖升高、呼吸节律改变、末梢循环差、双肺闻及啰音是HFM;;DOI:10.3969/j.issn.危重症发生的独立危险因素,是HFM;;DOI:10.3969/j.issn.危重症的早期预警指标。结论根据对重症HFM;;DOI:10.3969/j.issn.患者呼吸、心率、血压、血糖、末梢循环、双肺啰音的密切观察,能够对危重症的发生进行早期预警。
Objective To investigate the risk factors associated with critically ill hand-foot-mouth disease (HFM ;; DOI: 10.3969 / j.issn.) And to find the risk factors for HFM. DOI: 10.3969 / j.issn. Methods From March to September in 2010, 73 patients with HFM in Xinxiang Central Hospital were enrolled in this study. 90 children with severe HFM and 90 with severe HFM in Xinxiang Infectious Disease Hospital were enrolled in this study. Children’s clinical data for single factor and multivariate analysis. HFM ;; DOI: 10.3969 / j.issn. The diagnostic criteria are in accordance with the clinical diagnostic criteria of Handbook of Foot and Mouth Disease Diagnosis and Treatment Guide 2010 Edition issued by the Ministry of Health of China. The results of severe HFM ;; DOI: 10.3969 / j.issn. Children with critical illness before the onset of the following characteristics: persistent fever (≥ 39 ℃), apathetic or lethargy, limb jitter or tremor, high blood pressure, fast heart rate, High blood sugar, respiratory rhythm changes, poor peripheral circulation, peripheral white blood cell count increased, lung arousal and so on. Logistic regression analysis showed that high blood pressure, fasting blood glucose, elevated blood glucose, changes in respiratory rhythm, poor peripheral circulation and lung aneurysm were HFM; DOI: 10.3969 /j.issn. The independent risk factor for critical illness is HFM ;; DOI: 10.3969 / j.issn. Early warning indicator for critically ill patients. Conclusions The close observation of severe HFM; DOI: 10.3969 / j.issn. Patients with respiratory, heart rate, blood pressure, blood glucose, peripheral circulation, and pulmonary rales can provide early warning of critical illness.