目的了解医科大学生孤独状况,探讨孤独感与自尊的相互关系。方法采用状态与特质性孤独量表和自尊量表(SES)对500名医科大学生进行了评定。结果有相当多的医科大学生表示经常体验到孤独,医科大学生的孤独感在家在地、是否独生子女、家庭经济状况上差异显著而在性别上差异不显著。医科大学生的孤独分数与自尊显著负相关,自尊可以作为孤独的有效预测指标。结论自尊得分低的医科大学生其孤独得分高,医科高校的心理健康工作者要加强对大学生孤独心理的研究和干预。 Objective To understand the lonely status of medical college students and explore the relationship between loneliness and self-esteem. Methods Fifty-five medical undergraduates were assessed using the State and Trait Latent Scale and Self-Esteem Scale (SES). The results of a considerable number of medical students said they often experience loneliness, medical college students loneliness at home, whether or not only child, the family economy significantly different but not significantly different in gender. Medical students’ loneliness scores were significantly and negatively correlated with self-esteem, and self-esteem could be an effective predictor of loneliness. Conclusion Medical college students with low self-esteem scores have high scores of loneliness. Psychological health workers in medical colleges and universities should strengthen the research and intervention of college students’ loneliness.