输卵管阻塞性不孕症介入再通术后通畅率影响因素的Logistic回归分析

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目的研究输卵管阻塞性不孕症介入再通术后输卵管通畅率的影响因素。方法选择行输卵管阻塞性不孕症介入再通术患者100例,随机平均分为对照组和治疗组。术前调查年龄、病程、流产史、异位妊娠史等。两组手术方法相同,对照组疏通液包括地塞米松、庆大霉素、α-糜蛋白酶、生理盐水;治疗组增加复方丹参注射液。术后6个月复查输卵管选择性造影,比较术后通畅率与各因素的相关性。结果复查发现不同年龄、不同病程、有无流产史、有无异位妊娠史患者间通畅率无统计学差异(P>0.05)。治疗组通畅率显著高于对照组(P<0.05),无盆腔操作史者通畅率显著高于有盆腔操作史(P<0.05),原发性不孕症患者通畅率显著低于继发性不孕症患者(P<0.05),输卵管间质及峡部阻塞者通畅率最高(100.00%)、壶腹部次之(97.50%)、伞部最低(65.22%);治疗方法 (OR=3.823)、不孕症类型(OR=3.234)、阻塞部位(OR=3.527),盆腔操作史(OR=0.179)均与通畅率相关(P<0.05)。结论输卵管阻塞性不孕症介入再通术后通畅率与是否联合应用丹参注射液、有无盆腔操作史、原发性/继发性不孕、输卵管阻塞部位等因素相关;与年龄、病程、流产史、异位妊娠史无明显相关性。 Objective To study the influencing factors of tubal patency after interventional recanalization of tubal obstruction infertility. Methods 100 cases of tubal obstruction infertility interventional recanalization patients were randomly divided into control group and treatment group. Preoperative investigation of age, duration, abortion history, ectopic pregnancy history. Two groups of surgical methods the same, the control group to clear the fluid, including dexamethasone, gentamicin, α-chymotrypsin, saline; treatment group increased compound Salvia injection. Postoperative tubal selective imaging 6 months after surgery, the patency rate was compared with the various factors. The results of the review found that different ages, different duration, with or without abortion history, with or without ectopic pregnancy in patients with patency rate was no significant difference (P> 0.05). Patency rate was significantly higher in the treatment group than in the control group (P <0.05), patency without pelvic operation history was significantly higher than that with pelvic operation history (P <0.05), patency rate was significantly lower in patients with primary infertility than in secondary (100.00%), followed by the ampulla (97.50%) and the lowest part of the umbrella (65.22%). The treatment (OR = 3.823) The infertility type (OR = 3.234), obstruction site (OR = 3.527) and pelvic operative history (OR = 0.179) were all related to patency rate (P <0.05). CONCLUSIONS: The patency rate after interventional recanalization of tubal obstruction infertility is related to the combination of Danshen injection, history of pelvic operation, primary / secondary infertility and fallopian tube obstruction. The correlation between patency and age, course of disease, Abortion history, ectopic pregnancy history no significant correlation.
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