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目的分析观察中药内服配合克霉唑栓外用治疗复发性念珠菌性阴道炎的临床疗效。方法将76例患者随机分为2组,治疗组36例在对照组治疗基础上加用中药自拟方治疗。对照组38例采用克霉唑栓150mg阴道纳药治疗。结果治疗后3～7d、4周、8周2组总有效率比较,差异均无显著性意义(P>0.05),但停药第12周后2组总有效率比较,差异均有显著性意义(P<0.05)。经过12周治疗后,治疗组在随访期间复发3例,复发率为7.89%;对照组在随访期间内复发10例,复发率为26.32%,治疗组复发率低于对照组,差异有有统计学意义(P<0.05)。结论中药内服配合克霉唑栓外用治疗复发性念珠菌性阴道炎疗效确切,且能减少复发,改善临床症状,值得临床推广。
Objective To observe and observe the clinical efficacy of topical Chinese medicine combined with clotrimazole suppository in the treatment of recurrent candidal vaginitis. Methods A total of 76 patients were randomly divided into two groups. The treatment group (36 cases) was treated with traditional Chinese medicine (TCM) on the basis of the control group. 38 cases of control group received Clotrimazole suppository 150mg vaginal drug treatment. Results There was no significant difference in the total effective rate between the two groups at 3 ~ 7d, 4w and 8w after treatment (P> 0.05), but there was significant difference between the two groups after 12 weeks’ withdrawal Significance (P <0.05). After 12 weeks of treatment, the treatment group relapsed during follow-up in 3 cases, the recurrence rate was 7.89%; control group in the follow-up period of 10 cases of recurrence, the recurrence rate was 26.32%, the treatment group recurrence rate was lower than the control group, the difference was statistically Significance (P <0.05). Conclusion Chinese medicine oral administration of clotrimazole suppository for the treatment of recurrent Candida vaginitis is effective, and can reduce recurrence and improve clinical symptoms, it is worth clinical promotion.