各种病因的肝脏损伤都伴有肝星状细胞(HSC)的活化。活化HSC分泌大量的细胞外基质导致肝纤维化。探讨HSC的改变在肝纤维化恢复中的作用,将为肝纤维化的治疗提供方向。1HSC是参与肝纤维化的主要细胞在肝脏的慢性损伤过程中,HSC经历了一个称为“活化”的过程,有一系列的细胞和细胞 Hepatic stellate cells (HSCs) are activated by various causes of liver damage. Activated HSCs secrete large amounts of extracellular matrix leading to liver fibrosis. To investigate the role of HSC changes in the recovery of liver fibrosis will provide the direction for the treatment of liver fibrosis. 1HSC is a major cell involved in hepatic fibrosis During the chronic injury of the liver, HSCs undergo a process called activation that involves a series of cells and cells