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目的 总结乳腺癌术后局部复发和 (或 )远地转移的临床特点。方法 回顾性分析 6 6例术后首次复发和 (或 )远地转移乳腺癌的临床资料 ,6 6例病人均行手术治疗 ,其中单纯手术 (S) 2 1例 ,手术加放疗 (S +R) 7例 ,手术加化疗 (S +C) 2 0例 ,手术加化疗加放疗 (S +R +C) 18例。其中手术均为乳腺癌根治术或改良根治术。结果 全组 2年内复发和 (或 )远地转移占 74 2 % ,腋淋巴结转移数 <4及≥ 4的两组病例 ,胸壁复发率各为 2 2 2 %和 4 3 9% (P <0 0 5 ) ,曾行术后放疗和化疗的病例 ,局部复发率和远地转移率均低于未放化疗组。结论 对于腋淋巴结≥ 4的病人 ,放疗应加照患侧胸壁 ,术后适当的放化疗可以提高局控率 ,减少远地转移的发生。
Objective To summarize the clinical features of postoperative local recurrence and / or distant metastasis of breast cancer. Methods Sixty-six patients with primary recurrence and / or metastasis of breast cancer were retrospectively analyzed. Sixty-six patients underwent surgery, including 21 cases of simple operation (S), operation plus radiotherapy (S + R ) In 7 cases, 20 cases in operation plus chemotherapy (S + C) and 18 cases in operation plus chemotherapy plus radiotherapy (S + R + C). Surgery in which surgery are radical mastectomy or modified radical mastectomy. Results In the two groups, the recurrence and / or distant metastasis accounted for 74.2% within 2 years, the number of axillary lymph node metastasis <4 and ≥ 4, the rates of chest wall recurrence were 22.2% and 49.3% (P <0 0 5), who had undergone postoperative radiotherapy and chemotherapy cases, local recurrence rate and distant metastasis were lower than those without radiotherapy and chemotherapy group. Conclusion For patients with axillary lymph node ≥ 4, radiotherapy should be performed on the affected side of the chest wall. Appropriate radiotherapy and chemotherapy can improve the rate of local control and reduce the incidence of distant metastasis.