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目的 :采用动态血压监测仪观察非洛地平缓释片的降压疗效。方法 :非洛地平缓释片 5～ 10mg ,po ,qd× 2wk治疗 31例高血压病人 (男性 18例 ,女性 13例 ,年龄 53a±s 7a)。结果 :治疗前后2 4h平均血压、夜晚和白昼 (最高、最低 )的平均血压及血压负荷值自身对照比较差别有非常显著意义(P <0 .0 1)。降低收缩压和舒张压的谷/峰比值分别为 0 .64± 0 .2 3和 0 .70± 0 .2 2。结论 :非洛地平缓释片有较好谷/峰比值 ,提示该药每日 1次服法可在 2 4h内稳定控制血压
Objective: To observe the antihypertensive effect of felodipine sustained-release tablets by ambulatory blood pressure monitor. Methods: 31 cases of hypertensive patients (18 males and 13 females, age 53a ± s 7a) were treated with 5 ~ 10 mg, po and qd × 2 weeks of sustained release tablets of felodipine. Results: Mean blood pressure, nighttime and daytime (highest and lowest) mean blood pressure and blood pressure load self-control at 24 hours before and after treatment were significantly different (P <0.01). The reduction of systolic and diastolic valleys was 0.64 ± 0.23 and 0.70 ± 0.2 2, respectively. Conclusion: The felodipine sustained-release tablets have a good valley / peak ratio, suggesting that the drug once a day can stabilize blood pressure within 24 hours