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作者对有关增强非胰岛素依赖型糖尿病(NIDDM)病人体内胰岛素作用的切实可行治疗作了文献复习和总结。饮食大多数不需药物治疗的NIDDM病人是超重的,通过限制热卡使体重减轻,可以增强体内胰岛索的作用。糖耐量正常或受损的肥胖者,体重下降20磅可导致胰岛素作用增强近一倍。还有资料证实,患NIDDM的肥胖病人长期减轻体重,可使糖耐量恢复至接近正常。这种改善与血浆胰岛索对葡萄糖的反应增强有关。不同的饮食组成成份对体内胰岛素作用的影响仍不明确。适当改变饮食中碳水化合物的组成,虽不如限制热卡的治疗价值大,但也不容忽视。锻炼已知短时间的剧烈运动有降血糖的作用,而且有规律的锻炼常被视为治疗糖尿病的基本措施。在用链脲霉素所致的胰岛素中等缺乏的大鼠中,运动
The authors reviewed and summarized the literature on practical treatment of insulin in patients with non-insulin dependent diabetes mellitus (NIDDM). Diet Most NIDDM patients who do not need medication are overweight, and by limiting the heat card to lose weight, can enhance the role of islet in the body. Obese people with normal or impaired glucose tolerance, weight loss of 20 pounds can lead to an almost doubled effect of insulin. Data also confirmed that obese patients with NIDDM long-term weight loss, glucose tolerance can be restored to near normal. This improvement is associated with increased plasma islet glucocorticoid response. The effect of different diet components on insulin action in vivo remains unclear. Appropriate to change the composition of carbohydrates in the diet, although not as good as the treatment of heat card value, but can not be ignored. Exercise known strenuous exercise for a short time hypoglycemic effect, and regular exercise is often considered the basic treatment of diabetes measures. In streptozotocin-induced insulin-deficient rats, exercise