论文部分内容阅读
目的观察帕罗西汀辅助治疗风湿病合并抑郁障碍的疗效。方法对照组只采取抗风湿治疗;治疗组在抗风湿治疗的基础上,给予抗抑郁药物帕罗西汀共服药2个月。治疗2个月观察观察抑郁障碍、风湿病改善情况。结果8周后治疗组HAMD评分明显低于对照组,p<0.05;治疗组抑郁障碍改善情况优于对照组,p<0.05;风湿病改善状况亦优于对照组,p<0.05。结论帕罗西汀抗抑郁联合抗风湿治疗对风湿病伴抑郁障碍患者治疗效果,较单纯抗风湿治疗改善抑郁情绪效果好,从而提高患者对治疗的依从性和反应性,有效改善风湿病情。
Objective To observe the efficacy of paroxetine in the treatment of rheumatism complicated with depression. Methods The control group was treated with anti-rheumatism only. On the basis of anti-rheumatic treatment, the treatment group was treated with paroxetine, an anti-depressant, for 2 months. Treatment for 2 months observed depressive disorders, rheumatism to improve the situation. Results After 8 weeks, the HAMD score of the treatment group was significantly lower than that of the control group (p <0.05). The improvement of depression in the treatment group was better than that of the control group (p <0.05). The improvement of rheumatism was also better than that of the control group (p <0.05). Conclusions Paroxetine combined with anti-depression and anti-rheumatic therapy has a better curative effect on patients with rheumatism and depressive disorder than pure anti-rheumatic therapy, which can improve compliance and reactivity of the patients and effectively improve rheumatism.