论文部分内容阅读
目的了解成都市武侯区自然人群肥胖与大动脉僵硬度的关系。方法抽取5个居民小区,对居民登记、采集病史并行血压、血生化及臂踝脉搏波传导速度(baPWV)检查。比较体质量正常组与体质量过低、超重、肥胖组的血压、心率等心血管危险因素水平。并比较不同腰围水平组的心血管危险因素水平。用简单线性回归法分析各因素与baPWV的关系,多元线性回归法分析肥胖与baPWV的关系。结果资料齐全并纳入分析1339人(男634人,女705人)。超重或肥胖者的收缩压、舒张压、空腹血糖和三酰甘油等心血管疾病危险因素水平高于体质量正常组。腰围最低四分位组的心血管危险因素水平也较其余组低。对年龄、血压、血脂、血糖水平、吸烟、糖尿病等因素进行校正后,体质量指数(β=-0.086,P<0.001)和腰围(β=-0.046,P=0.038)均与baPWV呈负相关。结论成都市武侯区自然人群的体质量指数和腰围与大动脉僵硬度呈独立负相关。
Objective To understand the relationship between obesity and aortic stiffness in natural population in Wuhou District of Chengdu City. Methods A total of 5 residential areas were sampled and examined for resident registration, history of blood pressure acquisition, blood biochemistry and brachial-ankle pulse wave velocity (baPWV). Comparison of normal body weight and body weight is too low, overweight, obesity, blood pressure, heart rate and other cardiovascular risk factors. The levels of cardiovascular risk factors in different waistline groups were compared. The relationship between baPWV and baPWV was analyzed by simple linear regression, and the relationship between obesity and baPWV was analyzed by multivariate linear regression analysis. Results The data were complete and included 1339 people (634 males and 705 females). Overweight or obese systolic blood pressure, diastolic blood pressure, fasting blood glucose and triglyceride and other cardiovascular disease risk factors were higher than the normal weight group. The lowest risk of cardiovascular risk in the lowest quartile of waist circumference was also lower than the other groups. Body mass index (β = -0.086, P <0.001) and waist circumference (β = -0.046, P = 0.038) were negatively correlated with baPWV after adjusting for age, blood pressure, blood lipid, blood glucose level, smoking, diabetes and other factors . Conclusion Body mass index and waist circumference and aortic stiffness of the natural population in Wuhou District of Chengdu City are independently and negatively correlated.