本文复习了近年有关病例报告,对药物所致肺病的临床特点、X线表现及防治措施作一综述。1.细胞毒性药:博来霉素主要引起间质肺炎及肺纤维化、发生率为3～6%,其中致命性肺纤维化占1～2%,尤多见于70岁以上的老年患者及用药总量>450毫克的患者。该药与放疗或其他细胞毒性药合用或同时吸入高浓度氧时可使毒性增强。统计了115例用博来霉素(总量60～285毫克)合并胸照射 This article reviewed the recent case reports on the clinical features of pulmonary disease caused by drugs, X-ray findings and prevention and treatment are reviewed. 1. Cytotoxic drugs: bleomycin mainly caused by interstitial pneumonitis and pulmonary fibrosis, the incidence rate of 3 to 6%, of which 1 to 2% of fatal pulmonary fibrosis, especially seen in elderly patients over the age of 70 and The total amount of medication> 450 mg patients. The drug and radiotherapy or other cytotoxic drugs combined or inhalation of high concentrations of oxygen toxicity can be enhanced. Statistics of 115 cases with bleomycin (total 60 to 285 mg) combined with chest irradiation