目的了解职业人群布鲁杆菌病感染状况,为有效防治布鲁杆菌病提供科学依据。方法采用流行病学调查和血清抗体检测的方法进行调查。结果河北省职业人群布鲁杆菌病平均感染率为7.42%,各地区间感染率差异有统计学意义,张家口市最高(15.63%),廊坊市最低(2.86%);不同职业人群感染率存在显著差异,其中放牧人群感染率最高(10.60%),其次为屠宰(8.25%)和饲养人群(7.60%);感染者中新发现病例341例,旧病例269例,隐性感染者193例。结论河北省职业人群受布鲁杆菌病威胁严重。北部以牲畜饲养为主的地区、牲畜屠宰和皮毛加工集散地职业人群感染率较高;放牧、屠宰、饲养人群为布鲁杆菌病高危人群。 Objective To understand the prevalence of brucellosis in occupational population and provide a scientific basis for effective prevention and treatment of brucellosis. Methods Epidemiological survey and serum antibody test methods were investigated. Results The average prevalence rate of brucellosis among occupational population was 7.42% in Hebei Province. There was significant difference in the infection rates among different regions, with the highest in Zhangjiakou City (15.63%) and the lowest (2.86%) in Langfang City. The infection rates in different occupations were significantly different (10.60%), followed by slaughtering (8.25%) and breeding population (7.60%). Among newly infected cases, 341 cases were newly detected, 269 cases were old, and 193 cases were latent infection. Conclusion The occupational population in Hebei Province is seriously threatened by Brucella. In the north, where the livestock is the mainstay, the occupational population in the livestock slaughtering and fur processing distribution center has a higher infection rate; and the grazing, slaughtering and breeding populations are at high risk for brucellosis.