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利用傅里叶变换拉曼光谱仪得到了甲状腺癌和甲状腺正常组织样品的拉曼光谱,这2种组织样本的拉曼特征峰主要出现在400~3 500 cm-1的波长范围内。在甲状腺正常组织的拉曼光谱中位于503和758cm-1处有两个特征峰,758 cm-1处峰指认为苯环的环振动,503 cm-1处的拉曼峰经分析初步指认为C—Ⅰ伸缩振动,这2个特征峰在甲状腺癌的拉曼光谱中均消失。在甲状腺正常组织的拉曼光谱中位于3 062和1 003 cm-1处酪氨酸的特征峰,在甲状腺癌组织的拉曼光谱中,这2处峰的相对强度明显降低。因此,拉曼光谱法有望成为甲状腺癌诊断的有效方法。
The Raman spectrum of thyroid cancer and normal thyroid tissue samples was obtained by Fourier transform Raman spectroscopy. The Raman spectra of these two tissue samples mainly appeared in the wavelength range of 400-3 500 cm-1. There are two characteristic peaks at 503 and 758 cm −1 in the Raman spectrum of normal thyroid tissue. The 758 cm −1 peak refers to the ring vibration of the benzene ring. The Raman peak at 503 cm −1 is initially considered by analysis. C-I stretching vibration, these two characteristic peaks disappeared in the Raman spectrum of thyroid cancer. In the Raman spectra of normal thyroid tissues, characteristic peaks of tyrosine located at 3 062 and 1 003 cm −1 , the relative intensities of the two peaks were significantly reduced in Raman spectra of thyroid cancer tissues. Therefore, Raman spectroscopy is expected to be an effective method for the diagnosis of thyroid cancer.