血清25-(OH)D水平可以作为维生素D营养状况的客观指标,一般认为血清25-(OH)D≥75nmol/L是维生素D较为理想的水平。儿童是维生素D缺乏的潜在高危人群,维生素D缺乏不仅可使儿童患佝偻病,而且还与心脑血管疾病、呼吸系统疾病、自身免疫性疾病、肾脏疾病、神经精神疾病、肿瘤、糖尿病等密切相关。本文就此方面的研究进展进行系统综述。 Serum 25- (OH) D levels can be used as an objective indicator of the nutritional status of vitamin D. It is generally believed that serum 25- (OH) D ≧ 75nmol / L is the more ideal level of vitamin D. Children are potentially at risk of vitamin D deficiency. Vitamin D deficiency is not only associated with rickets in children, but also with cardiovascular and cerebrovascular diseases, respiratory diseases, autoimmune diseases, kidney diseases, neuropsychiatric diseases, cancer and diabetes . This article reviews the research progress in this area.