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目的对厄贝沙坦联合尼群地平对老年性高血压的临床疗效进行评价。方法取本院2016年2月份到2017年2月份收治的60例老年性高血压患者设为研究对象。分成两组,30例患者采用尼群地平进行治疗,设为对照组;30例患者采用厄贝沙坦联合尼群地平进行治疗,设为实验组。观察患者的治疗情况,并对患者临床疗效进行评估。结果实验组的总有效率较高,与对照组数据差异性明显,证实存在统计学意义,P<0.05;实验组的血压、心率改善情况较优,与对照组数据差异明显,证实存在统计学意义,P<0.05。两组患者均无严重不良反应发生,P>0.05。结论对老年性高血压患者采用厄贝沙坦、尼群地平进行联合治疗,对患者血压水平以及生活质量有显著改善效果。
Objective To evaluate the clinical efficacy of irbesartan and nitrendipine in senile hypertension. Methods Sixty elderly patients with hypertension who were treated in our hospital from February 2016 to February 2017 were enrolled in this study. Divided into two groups, 30 patients treated with nitrendipine as the control group; 30 patients treated with irbesartan combined nitrendipine, as the experimental group. Observe the treatment of patients, and evaluate the clinical efficacy of patients. Results The total effective rate of the experimental group was higher than that of the control group, which showed significant difference (P <0.05). The improvement of blood pressure and heart rate in the experimental group was better than that of the control group, and there was statistically significant Significance, P <0.05. No serious adverse reactions occurred in both groups, P> 0.05. Conclusions The combined treatment of irbesartan and nitrendipine in elderly patients with hypertension has significant effect on the patients’ blood pressure level and quality of life.