新生儿用药剂量是儿科用药的难点,临床在确定新生儿用药剂量时应注意以下几个问题。1.新生儿体内水分占体重的80%左右,且水分含量和分布与成人不同。因此,如按体重计算剂量,药物在体内浓度较低,剂量应相应增大;脱水状态下,药物在体液中易达到中毒浓度,要慎重用 Neonatal drug dosage is difficult for pediatric medication, clinical in determining the dosage of neonatal should pay attention to the following questions. 1. Neonatal body water accounts for about 80% of body weight, and moisture content and distribution and adults are different. Therefore, if the dosage is calculated according to the body weight, the concentration of the drug in the body is lower and the dose should be correspondingly increased; under the dehydrated state, the drug can easily reach the poisoning concentration in the body fluid and should be used with caution