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抗生素是从某些微生物(主要为放线菌)培养液中提取而对其他致病微生物有抑制或杀灭作用的一类化学物质。随着抗生素事业的迅速发展,新型抗生素不断问世,临床应用日趋广泛。回顾抗生素使用的历程,50年来确实在临床的抗感染、化疗中发挥了显著作用,已成为治疗细菌等微生物感染的重要药物。但是,抗生素的应用也存在着许多滥用或不合理用药的现象,如选药不当;对不良反应重视不足;耐药菌株日渐增多;不恰当的预防用药或联合用药等。为了正确地使用抗生素,本讲拟就有关抗生素合理应用的几个
Antibiotics are a class of chemicals that are extracted from the culture of certain microorganisms (mainly actinomycetes) and that inhibit or kill other pathogenic microorganisms. With the rapid development of antibiotics, new antibiotics continue to come out, the clinical application of an increasingly widespread. Review of the history of antibiotic use, 50 years has indeed played a significant role in clinical anti-infective, chemotherapy, has become an important drug for the treatment of microbial infections such as bacteria. However, there are many abuse or unreasonable use of antibiotics, such as improper drug selection, inadequate attention to adverse reactions, increasing number of drug-resistant strains, improper prophylaxis or combination therapy. In order to properly use antibiotics, this lecture on the rational use of antibiotics several