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通过采用罂粟碱的不同给药途径研究比较其对脑血管痉挛 (CVS)的防治效果。将 43例动脉瘤患者随机分成A、B两组 ,A组术中经置入脑池的硅胶管用罂粟碱溶液持续灌洗 ;B组术后使用罂粟碱 3 0mg肌肉注射 ,每日 3次 ,共 1周。结果显示 ,A组防治血管痉挛的效果明显优于B组。提示罂粟碱局部灌洗能有效防治脑动脉瘤术后血管痉挛
Through the use of papaverine in different routes of administration to compare its prevention and treatment of cerebral vasospasm (CVS). 43 patients with aneurysm were randomly divided into A, B two groups, A group of intraoperative silicone tube inserted into the cerebral pool with papaverine solution continued lavage; B group after intramuscular injection of papaverine 30mg 3 times a day, A total of 1 week. The results showed that A group of prevention and treatment of vasospasm was significantly better than the B group. Tip papaverine local lavage can effectively prevent cerebral aneurysm postoperative vasospasm