甲硝哒唑在临床上的抗阿米巴作用,促使许多作者寻找治疗阿米巴病的其他硝基咪唑衍生物的研究。本文报告对甲硝哒唑与另一硝基咪唑衍生物Ro7—0207进行的临床对比试验。20例无贫血和其他疾病的阿米巴痢疾患者,均有带有血液和粘液的腹泻,粪便中有吞噬红细胞的溶组织内阿米巴。随机将患者分为甲硝哒唑和Ro7—0207两组进行治疗。所用药物的剂型相同。儿童的疗程为7天,2～6岁每天125毫克,7～12岁每天250 The clinical anti-amoebic effect of metronidazole has prompted many authors to look at other nitroimidazole derivatives for the treatment of amebiasis. This article reports a clinical comparative study of metronidazole and another nitroimidazole derivative, Ro7-0207. Twenty patients with amebic dysthma without anemia and other illnesses had diarrhea with blood and mucus, and there were E. histolytica Entamoeba phagocytosis in the stool. Patients were randomly divided into metronidazole and Ro7-0207 two groups for treatment. The same dosage forms used. Children’s treatment for 7 days, 2 to 6 years old 125 mg daily, 7 to 12 years old 250