论文部分内容阅读
目的探讨彩色多普勒超声在慢性乙型肝炎肝纤维化诊断中的应用价值。方法选取2012年3月至2015年4月期间贵港市第二人民医院收治的256例慢性乙型肝炎患者,根据肝纤维化病理诊断结果分为S_0期(48例)、S_1期(52例)、S_2期(50例)、S_3期(64例)、S_4期(42例),同时选取46例健康体检人员作为对照组,均接受彩色多普勒超声检查,对比各组检查结果。结果门静脉内径(Dpv)及肝固有动脉峰值血流速度(HAV_(max))随肝脏纤维化的加重而明显增高(P<0.05),门静脉峰值血流速度(PVV_(max))随肝脏纤维化的加重而明显降低(P<0.05);不同肝脏纤维化分期之间脾动脉搏动指数(SPPI)比较差异无统计学意义(P>0.05),肝固有动脉血流峰值与门静脉血流峰值比(A/P)随肝脏纤维化的加重而明显增高(P<0.05),肝循环指数(HCI)随肝脏纤维化的加重而明显降低(P<0.05);S_3、S_4期肝静脉频谱异常率与对照组、S_0、S_1期比较差异均有统计学意义(P<0.05)。结论彩色多普勒超声用于慢性乙型肝炎肝脏纤维化的诊断及分期将具有重要临床价值。
Objective To investigate the value of color Doppler ultrasound in the diagnosis of chronic hepatitis B liver fibrosis. Methods From March 2012 to April 2015, 256 patients with chronic hepatitis B who were treated in Guigang Second People’s Hospital were divided into S 0 (48 cases) and S 1 (52 cases) according to the pathological diagnosis of liver fibrosis. , S_2 (50 cases), S_3 (64 cases) and S_4 (42 cases). Forty-six healthy subjects were selected as control group. All patients underwent color Doppler ultrasonography to compare the results of each group. Results The diameter of portal vein (Dpv) and peak hepatic artery (HAV max) were significantly increased with the increase of hepatic fibrosis (P <0.05). The peak PVP (PVV max) of portal vein with hepatic fibrosis (P <0.05). There was no significant difference in splenic artery pulsatility index (SPPI) between different hepatic fibrosis stages (P> 0.05). The ratio of hepatic intrinsic arterial blood flow peak to portal vein blood flow peak ( (P <0.05). The hepatic circulation index (HCI) was significantly decreased with the aggravation of hepatic fibrosis (P <0.05). The frequency of hepatic venous anomalies in S_3 and S_4 The control group, S_0, S_1 phase differences were statistically significant (P <0.05). Conclusion The application of color Doppler ultrasound in the diagnosis and staging of liver fibrosis in patients with chronic hepatitis B will have important clinical value.