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目的:探讨保存人羊膜移植治疗难治性眼表疾病的临床疗效。方法:对59例70眼翼状胬肉、角膜溃疡、眼烧伤、大泡性角膜病变、眼表肿物的患者采取保存羊膜移植手术治疗,随访观察术后疗效。结果:术后随访6~24个月,无一例感染,植片全部存活,无排斥反应发生。翼状胬肉者中4眼复发,复发率为5.71%,3眼烧伤者出现角膜结膜化,其余未见复发及并发症发生。结论:羊膜移植是目前治疗难治性眼表疾病较为理想的方法。
Objective: To investigate the clinical efficacy of preservative amniotic membrane transplantation in refractory ocular surface diseases. Methods: Fifty-nine patients with pterygium of 70 eyes, corneal ulcer, ocular burns, bullous keratopathy and ocular surface tumor were treated with preserved amniotic membrane transplantation. The follow-up effect was observed. Results: All patients were followed up for 6-24 months without any infection. The allografts survived without any rejection. 4 of the pterygium recurrence, the recurrence rate was 5.71%, 3 eyes had corneal conjunctival burns, no recurrence of the rest and complications. Conclusion: Amniotic membrane transplantation is the ideal method for the treatment of refractory ocular surface diseases.