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作者报导1例临床及病理均为典型的多毛细胞性白血病。该病人的肿瘤细胞含有抗酒石酸酸性磷酸酶(下称抗酒酸磷酶),但仍然证实是由T-淋巴细胞衍化而来,因为它与羊红细胞自行形成玫瑰花结,而缺乏补体受体或IgG的Fc碎片受体,缺乏胞膜结合Ig(免疫球蛋白)或胞浆Ig,并且在试管中不能合成Ig。病人男性33岁,两年来乏力,腹部不适且易出血,体检脾脏明显肿大,肝轻度肿大,淋巴结未扪及,骨髓干抽,骨髓活检发现有弥漫性典型的多毛细胞性白血病细胞浸润。血红蛋白8克%,红细胞压积24%,白细胞2,900/微升,血小板4.5万/微升。白细胞分类,中性多核26%,多毛细胞20%。血清蛋白电
The authors report a case of clinical and pathological typical hairy cell leukemia. The patient’s tumor cells contain tartrate-resistant acid phosphatase (hereinafter referred to as anti-tartaric acid phosphatase), but it is still confirmed to be derived from T-lymphocytes because it forms rosette with sheep erythrocytes and lacks complement receptor Or Fc fragment receptor of IgG, lacking membrane-bound Ig (immunoglobulin) or cytosolic Ig, and Ig can not be synthesized in vitro. The patient was 33 years old and had weakness in two years, abdominal discomfort and bleeding. The spleen was obviously swollen, the liver was swollen, the lymph nodes were not palpable, the bone marrow stem pumping and bone marrow biopsy found diffuse typical hairy cell leukemia cell infiltration . 8 grams of hemoglobin, hematocrit 24%, leukocyte 2,900 / microliters, platelets 45,000 / microliters. White blood cell classification, 26% of neutral multi-core, hair cells 20%. Serum protein electricity