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目的探讨氦-氖激光联合阿昔洛韦、甲钴胺治疗老年带状疱疹后遗神经痛的疗效。方法将76例老年带状疱疹病人随机分为试验组和对照组,各38例。对照组采用常规阿昔洛韦及甲钴胺治疗,试验组在对照组的基础上给予氦-氖激光治疗,比较两组各临床症状消退时间及疗效。结果 1个疗程结束后,试验组在止痛时间、结痂时间、皮疹消退时间方面均短于对照组(P<0.01),试验组痊愈率为52.6%,明显高于对照组的28.9%(χ2=4.41,P<0.05)。试验组后遗神经痛疼痛视觉模拟评分(visual analogue scale,VAS)与对照组相比明显降低(P<0.01),后遗神经痛疗效总有效率,试验组为92.1%,对照组为68.4%,试验组优于对照组(P<0.01)。结论氦-氖激光联合阿昔洛韦、甲钴胺早期干预治疗带状疱疹后遗神经痛疗效优于单用药物治疗。
Objective To investigate the curative effect of helium-neon laser combined with acyclovir and mecobalamin on the treatment of senile herpes zoster neuralgia. Methods 76 cases of elderly patients with herpes zoster were randomly divided into experimental group and control group, 38 cases each. The control group was treated with conventional acyclovir and mecobalamin. The experimental group was given He-Ne laser treatment on the basis of the control group, and the clinical symptoms of both groups were compared. Results After one course of treatment, the test group was shorter than the control group in terms of analgesic time, scab time and rash subsidence time (P <0.01). The cure rate in the test group was 52.6%, significantly higher than that in the control group (χ2 = 4.41, P <0.05). The visual analogue scale (VAS) of post-nociceptive pain in experimental group was significantly lower than that of control group (P <0.01), and the total effective rate of post-nociceptive analgesia was 92.1% in experimental group and 68.4% in control group , The experimental group was better than the control group (P <0.01). Conclusion He-Ne laser combined with acyclovir, mecobalamin early intervention in the treatment of postherpetic neuralgia better than single drug treatment.