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目的研究伽玛刀治疗脑转移瘤的疗效和并发症。方法对2010年1月至2013年12月间92例患者进行伽玛刀治疗。采用Leksell C型伽玛刀。肿瘤平均体积7.9cm3(0.5~19.7cm3)。伽玛刀治疗处方剂量为30~44Gy,50%的等剂量线包绕。对92例患者伽玛刀治疗后进行临床随访,随访时间为3~39个月(平均10个月)。结果随访92例中,完全缓解12例(13%),部分缓解39例(42.4%),无变化34例(37%),恶化7例(7.6%);肿瘤局部控制率为92.4%(85/92)。结论伽玛刀是治疗脑转移瘤安全有效的方法。
Objective To study the efficacy and complications of gamma knife in the treatment of brain metastases. Methods Ninety-two patients underwent gamma knife treatment from January 2010 to December 2013. Leksell C-type gamma knife. The average tumor volume was 7.9 cm3 (0.5-19.7 cm3). Gamma knife treatment prescription dose of 30 ~ 44Gy, 50% of the isodose line wrap. The clinical follow-up of 92 patients after gamma knife treatment was performed for 3 to 39 months (mean 10 months). Results The follow-up of 92 cases showed complete remission in 12 cases (13%), partial remission in 39 cases (42.4%), no change in 34 cases (37%) and worsening in 7 cases (7.6%). The local control rate was 92.4% / 92). Conclusion Gamma knife is a safe and effective method for the treatment of brain metastases.