论文部分内容阅读
目的探讨早期应用胰岛素治疗2型糖尿病血糖控制水平及对患者胰岛B细胞功能恢复的影响。方法将诊断为2型糖尿病的36例患者按胰岛素治疗疗程分成20d组和60d组,观察2组治疗前后血糖、胰岛素及C肽释放水平。结果 2组经胰岛素治疗后血糖均明显下降(P<0.05),餐后1h、2h胰岛素及C肽水平均增加(P<0.05),但60d组效果更明显。结论早期应用胰岛素治疗2型糖尿病能促进胰岛B细胞功能恢复,远期治疗效果更满意。
Objective To investigate the effect of early application of insulin on glycemic control of type 2 diabetes mellitus (T2DM) and the functional recovery of islet B cells. Methods Thirty-six patients diagnosed with type 2 diabetes were divided into 20d and 60d groups according to insulin therapy. The levels of blood glucose, insulin and C-peptide were observed before and after treatment. Results The blood glucose of both groups decreased significantly after insulin treatment (P <0.05). The levels of insulin and C peptide increased 1 h and 2 h after meal (P <0.05), but the effect was more obvious at 60 d. Conclusion Early application of insulin in type 2 diabetes mellitus can promote the recovery of islet B cell function, and the long-term treatment effect is more satisfactory.