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目的比较剖宫产术中不同比重罗哌卡因蛛网膜下腔阻滞麻醉的半数有效剂量。方法随机将择期在蛛网膜下腔神经阻滞麻醉下行剖宫产手术的单胎足月初产妇42例分为两组(n=21),玉组为0.5%重比重罗哌卡因(HR)组,Ⅱ组为0.5%轻比重罗哌卡因(LR)组,经L2,3间隙行蛛网膜下腔麻醉,比较不同比重的罗派卡因在孕产妇麻醉中半数有效剂量的比较。结果0.5%重比重罗派卡因腰麻的ED50为9.57mg,(95%CI为8.78~10.56mg),0.5%轻比重罗派卡因腰麻的ED50为9.78mg,(95%95CI为9.18-11.13),二者比较差异无统计学意义(>0.05)。结论0.5%重比重罗哌卡因和0.5%轻比重罗派卡因在剖宫产术中的ED50分别为9.57和9.78,比重因素在剖宫产术中对腰麻无影响。“,”Objective To determine the median ef ective does (ED50)of the Subarachnoid block in the Cesarean section.Methods Wil be randomly in subarachnoid nerve block anesthesia downlink cesarean section surgery singletons ful-term primipara 42 cases were divided into 2 groups (n=21),The concentration of 0.5%hyperbaric (group HR)and hypobaric ropivacaine (group LR).Subarachnoid anesthesia through the lumbar spine 2~3 clearance to contrast the Median ef ective dose(ED50)in the Cesarean section of ropivacaine.Results The ED95 and 95%CI were9.57mg(95%CI 8.78-10.56mg) for 0.5%hyperbaric ropivacaine and 9.78mg (95%CI 9.18~11.13mg),There was no statistical y significant dif erence comparison ( >0.05).Conclusion The proportion of factors has no ef ective in Cesarean section for Subarachnoid anesthesia.