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目的:对比HA/HAG方案治疗老年急性髓细胞白血病(AHL)的临床疗效。方法:将38例AML患者随机分成UA组(18例)与HAG组(20例)分别使用以上2种方案进行化疗,比较两组的临床疗效及不良反应。结果:与HA组比较HAG组完全缓解率高,骨髓抑制时间短,不良反应发生率及早期死亡率有明显降低,总有效率7 5.0%。结论:HAG方案治疗老年急性髓细胞白血病疗效较好,毒副反应轻,结合个体化治疗方案疗效将更理想。
Objective: To compare the clinical efficacy of HA / HAG regimen in the treatment of senile acute myeloid leukemia (AHL). Methods: Thirty-eight patients with AML were randomly divided into UA group (n = 18) and HAG group (n = 20). The above two regimens were used for chemotherapy. The clinical efficacy and adverse reactions of the two groups were compared. Results: Compared with HA group, the HAG group had a high complete remission rate, short bone marrow suppression time, adverse reaction rate and early mortality rate, with a total effective rate of 5.0%. Conclusion: The HAG regimen is effective in treating elderly patients with acute myeloid leukemia with mild side effects. Combined with individualized treatment, the curative effect will be more satisfactory.