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目的探讨氯吡格雷治疗不稳定型心绞痛的临床效果及价值。方法方便选取该院于2015年4月—2016年4月间收治的90例不稳定型心绞痛患者为研究对象,随机分为对照组和观察组,各45例。给予对照组常规治疗,给予观察组常规治疗基础上的氯吡格雷治疗,对比两种治疗模式的临床效果。结果观察组的治疗总有效率为95.56%,治疗后的心绞痛次数、纤维蛋白原、血小板指标分别为(2.1±1.2)次、(4.8±1.1)g/L、(161.0±66.0)×109/L,明显优于对照组,差异有统计学意义(P<0.05)。观察组治疗后的TC、TG、LDL-C、HDL-C水平分别为(2.7±0.6)、(0.6±0.1)、(1.7±0.3)、(1.8±0.4)mmol/L,均优于对照组,两组差异有统计学意义(P<0.05)。结论对不稳定型心绞痛患者实施常规治疗基础上的氯吡格雷治疗,疗效显著,值得推广和应用。
Objective To investigate the clinical effect and value of clopidogrel in the treatment of unstable angina pectoris. Methods Convenient 90 patients with unstable angina pectoris admitted from April 2015 to April 2016 in our hospital were randomly divided into control group and observation group, with 45 cases in each group. The control group was given routine treatment, and the observation group was treated with clopidogrel on the basis of conventional treatment, comparing the clinical effects of the two treatment modes. Results The total effective rate of observation group was 95.56%. The number of angina pectoris, fibrinogen and platelet index after treatment were (2.1 ± 1.2), (4.8 ± 1.1) g / L, (161.0 ± 66.0) × 109 / L, which was significantly better than the control group, the difference was statistically significant (P <0.05). The levels of TC, TG, LDL-C and HDL-C in observation group were (2.7 ± 0.6), (0.6 ± 0.1), (1.7 ± 0.3) and (1.8 ± 0.4) mmol / L respectively Group, the difference between the two groups was statistically significant (P <0.05). Conclusion Clopidogrel treatment based on conventional treatment in patients with unstable angina pectoris has significant curative effect and is worthy of popularization and application.