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自1866年,德国医生Zenker创用Pneumokoniosis(尘肺)这一名词以来已有一百余年,但对尘肺的定义还没有一致的看法。 下面谈谈个人的粗浅认识: 1.粉尘与尘肺的关系是一个相当复杂的问题。粉尘是致病因子,肺脏为作用对象(即靶)。致病因子怎样作用于靶才发病?这既取决于致病因子本身的性质、存在状态、颗粒大小、数量多少等,同时又取决于靶本身,肺脏
Since 1866, German physician Zenker has been using the term pneumoconiosis for more than a century, but there is no consensus on the definition of pneumoconiosis. The following talk about personal superficial understanding: 1. The relationship between dust and pneumoconiosis is a very complex issue. Dust is a virulence factor, the lungs as the role of the target (ie target). How pathogenic factors act on target pathogenesis? This depends on the nature of the pathogenic factor itself, the existence of state, particle size, the number of how much, but also depends on the target itself, the lungs