到目前为止,有不少报告提到皮质激素并用疗法对重症感染有效,但以双盲法的对照研究尚未得到证明。为此日本东京大学的宇塜良夫氏进行了实验研究,用小鼠作成实验模型,在同等条件下观察并用皮质激素的效果。实验模型是以ddY小鼠,雾化吸入肺炎杆菌B—54株而制成肺炎,小鼠在24小时后出现菌血症,72小时后死亡。在实验中观察 So far, there are many reports that corticosteroids and treatment of severe infections effective, but double-blind control study has not been proved. To this end, Tokyo, Japan, Yu Mi Lifu conducted an experimental study using mice as experimental model, under the same conditions and observe the effect of corticosteroids. The experimental model is based on ddY mice, aerosol inhalation of Klebsiella pneumoniae B-54 strains and made of pneumonia, mice after 24 hours of bacteremia, 72 hours after the death. Observed in the experiment