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目的 探讨坦索罗辛对肾输尿管结石体外冲击波碎石(ESWL)后结石排空和石街的影响.方法 80例肾或输尿管单发结石患者行ESWL后分为两组:对照组38例,每天口服左氧氟沙星0.5 g,共7 d;研究组42例,每日加服坦索罗辛0.4 mg.以治疗满30 d或结石排出为观察终点.观察结石排空率、排空时间、止痛药使用以及石街情况.结果 研究组总结石排空率高于对照组(92.5% vs.81.6%)、排空时间短于对照组[(5.8±2.7)d vs.(9.7±3.5)d](P<0.05).研究组需手术干预的石街占11.1%(1/9),而对照组为42.9%(3/7)(P<0.05).结论 坦索罗辛能促进肾输尿管结石ESWL治疗后的排出,尤其是大结石,并且有利于石街的自行排出.“,”Objective To evaluated the effect of tamsulosin on the stone clearance after electronic shock wave lithotripsy(ESWL) in patients with renal and ureteral calculi. Methods A total of 80 patients with solitary renal or ureteral calculus after ESWL was divided into two groups. The patients in group C(38 cases) received levofloxacin tablets 0. 5 g daily for one week and those in group T(42 cases)were given additional tamsulosin 0. 4 mg daily until stone clearance or for a maximum of 30 days. The stone clearance rate, clearance time, effect on the outcome of steinstrasse and analgesic requirement were recorded. Results The total clearance rate was higher in group T than that in group C(92. 5% vs. 81. 6% ) (P<0. 05). The average time of ston clearance was shorter in group T than that in group C [(5. 8±2. 7) d vs. (9. 7+3. 5) d](P<0. 05). Steinstrasse resolved spontaneously was 88. 8% in group T, which was higher than 57. 1% in group C(P<0. 05). Conclusion Tamsulosin as an adjuvent promotes stone clearance after ESML in patients with renal and ureteral calculi.