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目的:评价口服氨酚羟考酮治疗中重度晚期癌症患者内脏痛的疗效和安全性。方法:采用随机对照试验,将70例中重度晚期癌症内脏痛患者随机分为试验组和对照组,试验组口服氨酚羟考酮片(n=35),对照组口服缓释吗啡片(n=35);分别于用药后d1,3,7观察两组患者的镇痛效果和不良反应。结果:两组患者均获得良好的镇痛疗效,并且不良反应发生率较低。结论:氨酚羟考酮对于中重度晚期癌症内脏痛有良好的镇痛效果。
OBJECTIVE: To evaluate the efficacy and safety of oral oxycodone in the treatment of visceral pain in patients with moderate-advanced advanced cancer. Methods: A randomized controlled trial was conducted in 70 patients with moderate to severe advanced cancer visceral pain. Patients were randomly divided into test group and control group. The patients in the test group were given oral oxycodone (n = 35) = 35). The analgesic effects and adverse reactions of the two groups were observed after d1, 3 and 7 respectively. Results: Both groups had good analgesic efficacy and the incidence of adverse reactions was low. CONCLUSION: Oxycodone acetaminophen has a good analgesic effect on visceral pain in moderate-advanced advanced cancer.