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已有报告急性病毒性肝炎(AVH)患者血清中存在抑制淋巴细胞转化的血清抑制因子(SIF)。作者对81例(男52例、女29例,年龄29～86岁)AVH 患者(其中甲型肝炎10例,乙型肝炎58例、非甲非乙型肝炎13例)分别在发病后第1、4、8、24及52周检测SIF 并进行其他有关实验室检查,以观察 SIF活性与 AVH 预后的关系。结果:发病后6个月63例患者痊愈(Ⅰ组),HBsAg 均转为阴性,并出现抗-HBs、抗-HBc 及抗-HBe;18例患者转氨酶一直呈高水平(Ⅱ组),HBsAg 和 HBeAg 均阳性。发病后1年,Ⅰ组患者生化检验结果
Serum inhibitors of lymphocyte transformation (SIF) have been reported in the serum of patients with acute viral hepatitis (AVH). The authors of 81 cases (52 males and 29 females, aged 29 to 86 years) AVH patients (including 10 cases of hepatitis A, 58 cases of hepatitis B, 13 cases of non-A non-hepatitis B), respectively, after the onset of 1 , 4, 8, 24 and 52 weeks to detect SIF and other related laboratory tests to observe the relationship between SIF activity and prognosis of AVH. Results: Sixty-three patients recovered after 6 months (group Ⅰ), HBsAg turned negative and anti-HBs, anti-HBc and anti-HBe appeared; 18 patients had high ALT (Ⅱ group), HBsAg And HBeAg were positive. One year after onset, the biochemical test results of patients in group Ⅰ