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目的:分析不同抗生素治疗方案治疗轻度慢性盆腔炎临床疗效和经济成本。方法:选择2013年5月至2015年2月和平县妇幼保健院收治轻度慢性盆腔炎患者120例,随机分为A组、B组、C组。A组采取常规静脉用药方法,B组采取序贯疗法,C组采取序贯转换疗法。比较3组患者临床疗效、治疗费用、不良反应和复发率。结果:(1)C组总有效率对比A组总有效率、B组总有效率更高,复发率对比A组、B组更低,差异具有统计学意义(P<0.05)。(2)3组患者不良反应发生率相似(P>0.05)。(3)A组单人给药品成本费用为为170元,给药费用为50元;B组单人的给药成本费用为114.8元,给药费用为25元;C组单人药品成本为117.4元,给药费用为25元。其它的检查成本,住院成本3组一致。预测B组采用序贯治疗比常规A组节约3208元,C组采用转换治疗比A组节约3104元。结论:不同抗生素治疗方案治疗轻度慢性盆腔炎临床疗效和经济成本不一。其中,序贯转换疗法的效果,预后复发情况优于常规静脉用药方法、序贯疗法,经济成本低于静脉用药方法,具有良好疗效-成本效益。
Objective: To analyze the clinical efficacy and economic cost of different antibiotic treatment for mild chronic pelvic inflammatory disease. Methods: One hundred and twenty patients with mild chronic pelvic inflammatory disease who were admitted to Heping County Maternal and Child Health Hospital from May 2013 to February 2015 were randomly divided into A, B and C groups. A group to take conventional intravenous drugs, B group to take sequential therapy, C group to take sequential conversion therapy. Clinical efficacy, treatment costs, adverse reactions and recurrence rates were compared between the three groups. Results: (1) The total effective rate of group C was higher than that of group A, and the total effective rate of group B was higher. The recurrence rate was lower in group A and group B than in group B (P <0.05). (2) The incidence of adverse reactions in the three groups was similar (P> 0.05). (3) The cost of single drug in group A was 170 yuan, the cost of drug was 50 yuan; the cost of single drug in group B was 114.8 yuan and the cost of drug was 25 yuan; the cost of single drug in group C was 117.4 yuan, medication costs 25 yuan. Other examination costs, hospitalization costs 3 groups. Predicting group B using sequential treatment saves 3208 yuan compared with conventional group A, C group using conversion treatment saves 3104 yuan more than group A. Conclusion: Different antibiotics treatment of mild chronic pelvic inflammatory disease clinical efficacy and economic costs vary. Among them, the effect of sequential conversion therapy, recurrence of prognosis is superior to conventional intravenous medication, sequential therapy, the economic cost is lower than the intravenous medication, with good efficacy - cost-effectiveness.